Dramatic response in the dependency to transfusion after low doses of lenalidomide treatment in a 5q-syndrome patient: a case report
1Department of Hematology, Pamukkale University Faculty of Medicine, Denizli, Turkey
Northern Clinics of Istanbul 2014; 3(1): 191-193 PubMed ID: 28058331 PMCID: PMC5175043 DOI: 10.14744/nci.2014.36036
Abstract
5q-syndrome is a special subgroup of myelodysplastic syndrome in terms of follow-up and treatment. Lenalidomide is an immunomodulatory drug that is frequently used in the treatment of multiple myeloma. Some clinical studies have shown that lenalidomide treatment is effective in 5q syndrome and significantly decreases the transfusion dependency in these patients. In this paper, we would like to share a dramatic response of lowered transfusion dependency after treatment with low-dose lenalidomide in a patient who received myelodysplastic syndrome diagnosis and isolated 5q anomaly in our clinic.
Keywords: del(5q), Lenalidomide; myelodysplastic syndrome.